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Decrease Toxic Metal Residues in Medicine (N-Heterocyclic Phosphines)

Invention SummaryThe invention is a new synthetic method for generation of P-C bonds (phosphorus-carbon bonds) with transition-metal-free reaction conditions. Phosphorus carbon bonds are often found in pharmaceuticals and antimicrobial natural products. Accordingly, creation of P-C bonds under metal-free reaction conditions would be highly desirable...

Published: 6/11/2015 | Inventor(s): Kyle Aleshire, Jun Yong Kang, Karimulla Mulla

Keywords(s): Biotech, Chemistry

Category(s): Chemistry, All, Therapeutics, Pharmaceuticals, Drug Delivery

New Biomarkers and Drug Repurposing for Patients with Alzheimer's Disease

Invention SummaryA set of 221 mutations in human genes that are present in all 724 genomes of humans with Alzheimer’s disease, but not present or present only 1 time in 1092 genomes of normal people. These can be used as biomarkers to identify those patients with a high likelihood of getting late onset Alzheimer’s disease (LOAD). Market...

Published: 7/1/2015 | Inventor(s): Jefferson Kinney, Martin Schiller

Keywords(s): Biotech, Imaging, Medical Devices, Pharmaceutical

Category(s): Life Sciences, Therapeutics, Pharmaceuticals, Drug Delivery, All