Multimodal tissue perfusion assessment and monitoring device


The Invention: 

Current methods of planning and monitoring are not only expensive and limited but often consume significant amounts of physicians’ limited time. In an ideal world, a device would automatically localize the blood vessels within the tissue to be transferred pre-op with minimal physician time or energy input, and monitoring would be performed across a maximal portion of the flap and continuously using modalities emulating critical aspects of a physical exam (e.g. temperature, color, size/contour), as well as modalities that go beyond qualities that can be detected by a human observer (e.g. high thermal, spatial, and temporal resolution/thermal mapping, terahertz radiation signature). Lower costs of these two steps would be an additional advantage in this hypothetical ideal world.


  • Uses multiple imaging modalities to improve accuracy/reliability 
  • Novel imaging modalities
  • Utilizes AI to identify tissue characteristics predictive of vascular compromise/tissue changes earlier than other modalities
  • Applies to Microsurgery planning, assessment, monitoring; wound care; vascular surgery and vasculopathy care; diabetes and chronic leg wound and edema care; trauma/extremity salvage

Market Opportunity: 

  • The medical device manufacturing market is currently $49.8 billion and is expected to grow at a CAGR of 3% to $57.7 billion by 2028. The air purification equipment manufacturing market is currently $7.6 billion and is expected to grow at a CAGR 1.3% to $8.1 billion by 2028.

Intellectual property:

  • Concept
Patent Information:
For Information, Contact:
Zachary Miles
Associate Vice President for Technology & Partnerships
University of Nevada, Las Vegas
Barry Claman
John Menezes
Marc Kahn
Brendan Morris
Computer Science & Software
Engineering & Manufacturing - Mechanical Engineering
Life Science
Med Devices, Diagnostics & Healthtech
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